Quality Control
Functionality tested in Real-time PCR for specificity, sensitivity and reproducibility for primer set using Breast cancer cell lines and samples.
HER-2/ESR1/PGR assay Service
NanoCinna Pharmacogenomics Center
HER-2/ESR1/PGR
The development of optimized therapy strategies against malignant tumors is critically dependent on the assessment of tissue-based biomarkers in routine diagnostic tissue samples. NanoCinna uses RT-PCR based on Carcinnotype assay to determine the RNA expression of the receptor genes below. These results may differ from ESR1, PGR , or HER2 results reported using other methods.
ESR1 score: <6.5 as negative, >=6.5 as positive
PGR score: <5.5 as negative, >=5.5 as positive
Her2 score: <10.7 as negative, equivocal range from 10.7 to 11.4 units and >=11.5 as positive
Application
Quantification of HER-2, ESR1 and PGR
expression
Sampling Condition
Paraffin-embedded, formalin-fixed breast
cancer tissue block at 20-25°C needed.
Only tissue that is clearly carcinoma
(established by histological criteria)
should be tested, for more information
please contact us.
Catalog Number
#S1372 HER-2, ESR1 and PGR assay
#S1384 description
Target genes: HER-2, ESR1 and PGR
Reference genes: ACTB, GAPDH, GUS, RPLPO, and TFRC
